Medical-Grade Nano Hydroxyapatite Particle Specifications and Enamel Integration
The APAGARD PREMIO enamel repair service toothpaste with nano hydroxyapatite uses crystalline calcium phosphate fragments [Ca10(PO4)6(OH)2] manufactured at nanometer range with typical diameter of 50-100 nanometers, allowing penetration into enamel micropores and subsurface demineralized zones gauging 1-10 micrometers deepness. This bit dimension matches the dimensional scale of enamel crystallite structure, assisting in ionic bonding and lattice combination instead of shallow surface layer. The APAGARD PREMIO remineralizing toothpaste for enamel security operates via three-phase system: first fragment adsorption onto enamel surface area through electrostatic destination occurring within 30-60 seconds of get in touch with, diffusion right into subsurface sores over 1-2 minute cleaning duration, and continual mineral ion launch during 4-6 hour post-application duration as particles gradually dissolve in acidic oral environment (pH 5.5-6.5).
Nano-mHAP bit surface procedures 200-300 m ²/ g, providing substantial reactive user interface for calcium and phosphate ion exchange with saliva and enamel substratum. The APAGARD PREMIO lightening tooth paste for dull teeth optical brightening mechanism reduces enamel surface area roughness (Ra) from typical 0.8-1.2 micrometers in used enamel to 0.3-0.5 micrometers after 4 weeks of twice-daily application, as evaluated by atomic force microscopy dimensions. This smoothing eliminates microscale surface abnormalities that scatter event light, increasing specular reflection coefficient from 15-25% (rough enamel) to 40-55% (smooth enamel), producing shiny look without chemical bleaching agents like hydrogen peroxide or carbamide peroxide that permeate enamel framework through oxidative devices. The APAGARD PREMIO toothpaste for dental caries defense and fresh breath antimicrobial residential properties stem from fragment adsorption of microbial cells and proteins onto nano-mHAP surface, decreasing planktonic germs focus in saliva by 30-50% and preventing biofilm formation through competitive surface profession on enamel pellicle layer.
PREMIO Premium Concentration Formulations and Clinical Efficacy
The APAGARD PREMIO toothpaste for enamel remineralization and shine includes 10-12% nano-mHAP by weight, representing premium focus rate that increases remineralization kinetics contrasted to typical 7-9% formulas. Scientific efficiency researches making use of Vickers microhardness screening at 200-gram tons demonstrate 15-25% firmness recuperation in unnaturally demineralized enamel over 28-day test periods, with imprint depth reducing from 80-100 micrometers (demineralized state) to 60-75 micrometers (remineralized state). The APAGARD PREMIO toothpaste for gentle whitening and stain control rough system utilizes moisturized silica at 15-20% concentration with Family member Dentin Abrasivity (RDA) worth of 90-110, supplying adequate mechanical activity for extrinsic stain removal from chromogenic substances (coffee tannins, tea polyphenols, red wine anthocyanins) while continuing to be below 150 RDA threshold related to too much enamel wear over prolonged usage durations exceeding 5 years.
Those who buy APAGARD PREMIO toothpaste pack of 2 receive product packaging configuration giving 8-12 week supply for individual user at twice-daily application frequency (1.5-2.0 gram per session), enabling consistent remineralization impact throughout the 4-8 week duration required for quantifiable enamel microhardness recuperation as validated by research laboratory testing procedures. The APAGARD PREMIO tooth paste pack of 2 tube style keeps paste thickness of 80,000-120,000 centipoise at 25 ° C, exhibiting non-Newtonian shear-thinning habits where evident viscosity lowers from 100,000 cP at rest to 5,000-10,000 cP under brushing shear rates (100-1000 s ⁻¹), helping with brush loading and interdental penetration.
Manufacturing Specifications and Quality Control Parameters
The APAGARD Sangi nano hydroxyapatite tooth paste manufacturer designation recommendations exclusive synthesis process producing nano-mHAP bits with regulated crystalline morphology and narrow size circulation (coefficient of variant <15%), making sure consistent area and remineralization reactivity across manufacturing sets. The APAGARD Japan hydroxyapatite tooth paste manufacturing criteria follow Japanese pharmaceutical policies for medical-grade hydroxyapatite purity going beyond 99.5% Ca10(PO4)6(OH)2 with trace impurities limited to calcium oxide <0.3% and calcium carbonate <0.2%, ensuring biocompatibility and foreseeable remineralization kinetics. X-ray diffraction analysis confirms crystalline structure matching stoichiometric hydroxyapatite with calcium-to-phosphate molar ratio of 1.67, verifying material identification and mineral assimilation capacity with natural enamel matrix.
M-Series Requirement Concentration Specifications and Daily Upkeep
The APAGARD M fluoride totally free tooth paste addresses consumer sectors preventing fluoride as a result of dental fluorosis worries in young children (ages 0-6 years) where too much fluoride intake throughout enamel growth creates subsurface hypomineralization, or people liking biomimetic remineralization methods that bring back enamel structure without converting hydroxyapatite to fluorapatite [Ca10(PO4)6F2] The APAGARD M nano hydroxyapatite tooth paste has 7-9% nano-mHAP by weight, ideal for everyday enamel upkeep in individuals without substantial existing demineralization or surface area wear requiring sped up remineralization kinetics. The APAGARD M nano mHAP tooth paste bit size warehouse on 80-100 nanometer average diameter, enhanced for micropore penetration while maintaining stable suspension in dentifrice base throughout 36-month life span at space temperature storage space (20-25 ° C).
The APAGARD M enamel remineralization toothpaste solution consists of sorbitol (40-50% by weight) as humectant maintaining paste wetness material at 25-30%, avoiding desiccation-induced viscosity rise or particle aggregation. The APAGARD M enamel protection tooth paste preservative system utilizes sodium benzoate (0.1-0.3%) keeping microbiological security with microbial count below 10 CFU/g over storage period, fulfilling pharmaceutical-grade standards for dental care items. The APAGARD hydroxyapatite toothpaste product line enables option based on particular remineralization needs: PREMIO formulations with 10-12% nano-mHAP concentration match users with moderate enamel demineralization from nutritional acid direct exposure, while M-series formulas with 7-9% focus provide maintenance-level defense for individuals with undamaged enamel seeking precautionary care against future demineralization events.
The APAGARD nano hydroxyapatite technology utilizes fragments matching all-natural enamel mineral make-up, allowing straight mineral replacement via physical deposition instead of chemical conversion paths. The APAGARD enamel remineralization device achieves measurable microhardness healing through continual calcium and phosphate ion release from transferred fragments over 4-6 hour durations complying with application. The APAGARD enamel fixing tooth paste loads tiny surface abnormalities via preferential fragment deposition in surface area valleys and issues, with scanning electron microscopy at 5,000-10,000 × zoom showing particle integration. The APAGARD natural whitening tooth paste achieves optical lightening up via surface smoothing coming close to 0.1-0.2 micrometer Ra worths of undamaged enamel without altering inherent tooth shade.
Fluoride-Free Formula Chemistry and Security Account
The APAGARD fluoride cost-free tooth paste solution security maintains nano-mHAP suspension without opting for 18-24 months under typical storage problems, with xanthan periodontal (0.5-1.0%) providing thixotropic buildings that facilitate particle resuspension with tube squeezing activity. The APAGARD tooth paste for the whole family safety account throughout age ranges originates from nano-mHAP’s biocompatibility, as consumed bits undertake dissolution in stomach acid (pH 1.5-3.5) releasing calcium and phosphate ions that the body processes through regular mineral homeostasis pathways without systemic poisoning worries. Those that buy APAGARD M nano hydroxyapatite toothpaste obtain formula suitable for kids aged 2 years and above under parental guidance, with recommended dosage lowered to 0.3-0.5 gram (rice grain size) for ages 2-6 years to reduce consumption quantity.
Application Procedures and Relative Performance Evaluation
The APAGARD M toothpaste for daily enamel protection ideal application method defines modified Bass method with 45-degree bristle angle to gingival margin, round activities covering 2-3 teeth per location, and 2-3 minute overall duration preserving brushing force below 150 grams to avoid enamel abrasion. The APAGARD M toothpaste with nano mHAP for enamel care post-brushing protocol recommends expectoration without water rinsing to keep elevated calcium and phosphate ion focus in saliva from recurring nano-mHAP particles, expanding remineralization activity. The APAGARD M enamel remineralization toothpaste for everyday usage surfactant system utilizes sodium lauryl sulfate (1-2%) providing sufficient foaming and particles removal while staying listed below concentrations over 2.5% related to dental mucosa irritability.
The APAGARD M fluoride cost-free tooth paste for gentle brushing pH barrier system utilizes salt phosphate maintaining pH 6.5-7.5 throughout service life, avoiding nano-mHAP fragment aggregation below pH 6.0 or dissolution above pH 8.0 that would certainly compromise effectiveness. The APAGARD M tooth paste for family enamel support solution consists of moisturized silica with RDA value of 80-100 preventing extreme enamel wear while offering adequate mechanical action for plaque and particles elimination. The APAGARD Sangi APAGARD tooth paste with nano hydroxyapatite production process includes wet-milling of manufactured nano-mHAP in aqueous suspension to damage accumulations and accomplish target fragment dimension distribution. The APAGARD Japanese nano hydroxyapatite tooth paste for enamel production utilizes quality assurance screening consisting of fragment dimension evaluation by vibrant light scattering, crystallinity verification by X-ray diffraction, and pureness analysis by inductively coupled plasma mass spectrometry. Extra technical requirements and application support are available at http://theapagard.com/ for individuals calling for detailed info on nano-mHAP remineralization technology and ideal cleaning methods.